Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 13/20 | 0.75 |
| ▸ | EGFR | P00533 | 6/20 | 0.75 |
| ▸ | INSR | P06213 | 4/20 | 0.75 |
| ▸ | IGF1R | P08069 | 4/20 | 0.75 |
| ▸ | AURKA | O14965 | 1/20 | 0.75 |
| ▸ | ROS1 | P08922 | 1/20 | 0.75 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.75 |
| ▸ | MET | P08581 | 1/20 | 0.64 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059813 | 0.90 | ALK (0.65) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL29059835 | 0.90 | ALK (0.76) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL26611528 | 0.90 | EGFR (0.79) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL22518894 | 0.89 | EGFR (0.80) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL29045206 | 0.89 | EGFR (0.82) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL31276988 | 0.88 | EGFR (0.78) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL28033932 | 0.87 | ALK (0.77) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL21846979 | 0.87 | EGFR (0.78) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL26611761 | 0.86 | EGFR (0.73) | ALKEGFRINSRIGF1RAURKA | |
| SCHEMBL21846992 | 0.86 | EGFR (1.00) | ALKEGFRINSRIGF1RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386266-B | Pyrimidine derivatives having cancer cell growth inhibiting effect and pharmaceutical compositions containing the same | 昂科比克斯有限公司 | 2023-08-04 | — | — | CN | disclosed |