Saccharin

Saccharin

SCHEMBL28033936

CCCO.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 9/20 0.73
CA9 Q16790 9/20 0.73
CA2 P00918 7/20 0.73
CA1 P00915 3/20 0.73
KDM4E B2RXH2 2/20 0.73
CA7 P43166 2/20 0.73
USP2 O75604 1/20 0.73
LMNA P02545 1/20 0.73
BCHE P06276 1/20 0.73
CA4 P22748 1/20 0.73
CA6 P23280 1/20 0.73
CA5A P35218 1/20 0.73
KMT2A Q03164 1/20 0.73
CA14 Q9ULX7 1/20 0.73
CA5B Q9Y2D0 1/20 0.73
ALDH1A1 P00352 3/20 0.52
HSD11B1 P28845 1/20 0.45
CHEK1 O14757 1/20 0.44
DAPK3 O43293 1/20 0.44
MAP4K4 O95819 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL8061288 0.93 CA12 (0.79) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27519752 0.92 CA12 (0.67) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL5675345 0.92 CA12 (0.76) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL8024547 0.91 CA12 (0.81) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28202147 0.88 CA12 (0.76) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27538830 0.88 CA12 (0.81) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27848168 0.88 CA12 (0.88) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL28422430 0.87 CA12 (0.73) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27642958 0.86 CA12 (0.85) CA12CA9CA2CA1KDM4E
Saccharin SCHEMBL27387484 0.86 CA12 (0.85) CA12CA9CA2CA1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107456929-B Preparation method and application of monodisperse polysaccharide derivative microspheres 大连理工大学 2020-06-02 CN claimed
CN-107456929-B Preparation method and application of monodisperse polysaccharide derivative microspheres 大连理工大学 2020-06-02 CN disclosed
CN-104910691-A Water-Based Ink for Ink-Jet Recording, Ink Box, Water-Based Ink Set for Ink-Jet Recording, Treatment Agent And Box BROTHER IND LTD 2015-09-16 CN disclosed