Saccharin

Saccharin

SCHEMBL28202147

O=C1NS(=O)(=O)c2ccccc21.OCCCCO

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.76
CA9 Q16790 8/20 0.76
CA2 P00918 7/20 0.76
CA1 P00915 4/20 0.76
CA7 P43166 3/20 0.76
CA4 P22748 2/20 0.76
KDM4E B2RXH2 1/20 0.76
USP2 O75604 1/20 0.76
LMNA P02545 1/20 0.76
BCHE P06276 1/20 0.76
CA6 P23280 1/20 0.76
CA5A P35218 1/20 0.76
KMT2A Q03164 1/20 0.76
CA14 Q9ULX7 1/20 0.76
CA5B Q9Y2D0 1/20 0.76
ALDH1A1 P00352 2/20 0.54
HSD11B1 P28845 1/20 0.46
RET P07949 2/20 0.45
GRK5 P34947 2/20 0.45
TYRO3 Q06418 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL8024547 0.93 CA12 (0.81) CA12CA9CA2CA1CA7
Saccharin SCHEMBL27519752 0.91 CA12 (0.67) CA12CA9CA2CA1CA7
Saccharin SCHEMBL28033936 0.88 CA12 (0.73) CA12CA9CA2CA1CA7
Saccharin SCHEMBL8061288 0.88 CA12 (0.79) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29037506 0.87 CA12 (0.92) CA12CA9CA2CA1CA7
Saccharin SCHEMBL28045129 0.87 CA12 (0.92) CA12CA9CA2CA1CA7
Saccharin SCHEMBL3816 0.87 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29191365 0.87 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL6033672 0.87 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL588640 0.87 CA12 (1.00) CA12CA9CA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107898686-B Agar extract, preparation method and application thereof in cosmetics 扬州市华星化妆品有限公司 2020-12-11 CN claimed
CN-107898686-A A kind of rare flower extract and preparation method and its application in cosmetics 扬州市华星化妆品有限公司 2018-04-13 CN claimed
CN-107898686-B Agar extract, preparation method and application thereof in cosmetics 扬州市华星化妆品有限公司 2020-12-11 CN disclosed
CN-107898686-B Agar extract, preparation method and application thereof in cosmetics 扬州市华星化妆品有限公司 2020-12-11 CN disclosed
CN-107898686-A A kind of rare flower extract and preparation method and its application in cosmetics 扬州市华星化妆品有限公司 2018-04-13 CN disclosed
CN-107898686-A A kind of rare flower extract and preparation method and its application in cosmetics 扬州市华星化妆品有限公司 2018-04-13 CN disclosed