Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29446949 | 1.00 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28034038 | 1.00 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29446948 | 1.00 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL29446950 | 1.00 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7880809 | 1.00 | HPGD (0.47) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL30336486 | 0.86 | KMT2A (0.54) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28994501 | 0.86 | KMT2A (0.54) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27483440 | 0.83 | HPGD (0.55) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4585320 | 0.81 | HPGD (0.43) | HPGDRAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11150836 | 0.81 | RAB9A (0.56) | HPGDRAB9ANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393428-B | Preparation method of rivaroxaban impurity | 南京国星生物技术研究院有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-111393428-A | Method for preparing rivaroxaban impurity | 南京国星生物技术研究院有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-104961646-A | Mosapride active metabolites, preparation method and uses thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | disclosed |