Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585324 | 0.83 | HPGD (0.44) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL27483440 | 0.83 | HPGD (0.55) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL7880809 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL28034036 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL29446950 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL29446948 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL29446949 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL28034038 | 0.81 | HPGD (0.47) | HPGDL3MBTL1ALOX15HSD17B10KDM4E | |
| SCHEMBL9479764 | 0.79 | KDM4E (0.39) | HPGDL3MBTL1KDM4EALDH1A1LMNA | |
| SCHEMBL11167276 | 0.78 | HPGD (0.48) | HPGDALDH1A1GAATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | claimed |
| US-20080275065-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-11-06 | — | — | US | disclosed |
| EP-1802611-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | Syngeta Participations AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040113-A2 | HETEROCYCLIC DIAMIDE INSECTICIDAL AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275065-A1 | Novel Insecticides | DDT, ACHE, CYP4F11 | HPGD 3785/4885L3MBTL1 1598/4885ALOX15 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.