Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988538 | 0.90 | ALDH1A1 (0.52) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL16194313 | 0.80 | HPRT1 (0.56) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL11726972 | 0.80 | TRPM4 (0.68) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL13794246 | 0.78 | IDO1 (0.47) | TRPM4ALDH1A1HSD17B10IDO1HPGD | |
| SCHEMBL28059159 | 0.77 | TRPM4 (0.59) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL888299 | 0.76 | ALDH1A1 (0.68) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL16194204 | 0.74 | HPRT1 (0.58) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL27760500 | 0.74 | TRPM4 (0.65) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A | |
| SCHEMBL16194255 | 0.74 | HPRT1 (0.58) | ALDH1A1HSD17B10CYP1B1HIF1AHPRT1 | |
| SCHEMBL25412286 | 0.74 | ALDH1A1 (0.65) | TRPM4ALDH1A1HSD17B10CYP1B1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961675-A | Preparation method of isavuconazole intermediate | CHENGDU SYNS PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-104961675-A | Preparation method of isavuconazole intermediate | CHENGDU SYNS PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |