Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.67 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | NQO2 | P16083 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726972 | 0.96 | TRPM4 (0.68) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL31171122 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL25412286 | 0.88 | ALDH1A1 (0.65) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL7245676 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL23912230 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL27624854 | 0.82 | HSD17B10 (0.70) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| Dibenz[A,H]Anthracene SCHEMBL156100 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| Dibenz[A,H]Anthracene SCHEMBL29777008 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| Dibenz[A,H]Anthracene SCHEMBL29392838 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 | |
| SCHEMBL4856624 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HIF1ACYP1B1TRPM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514893-A | Steroid compound, preparation method and application thereof | 珂阑(上海)医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-107109056-A | Resin film formation composition and resin film | 日产化学工业株式会社 | 2017-08-29 | — | — | CN | disclosed |
| US-9676907-B2 | Methods and systems of graft polymerization on a functionalized substrate | ASPEN RESEARCH CORPORATION (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160168331-A1 | METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-16 | — | — | US | disclosed |
| US-9267009-B2 | Methods and systems of graft polymerization on a functionalized substrate | ASPEN RESEARCH CORPORATION (US) | 2016-02-23 | — | — | US | disclosed |
| CN-105061509-A | Ligands and catalyst systems thereof for the catalytic oligomerization of olefinic monomers | SHELL INT RESEARCH | 2015-11-18 | — | — | CN | disclosed |
| US-9073810-B2 | Catalyst systems for the catalytic oligomerization of olefinic monomers | SHELL OIL COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| US-9073809-B2 | Catalyst systems for the catalytic oligomerization of olefinic monomers | SHELL OIL COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| US-20140296366-A1 | METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE | ASPEN RESEARCH CORPORATION (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140296339-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | ACADIA PHARMACEUTICALS INC. | 2014-10-02 | — | — | US | disclosed |
| US-20090018200-A1 | COMPOSITION CONTAINING A PHENANTHRENOL | L'OREAL (FR) | 2009-01-15 | — | — | US | disclosed |
| WO-2008077908-A1 | LIGANDS AND CATALYST SYSTEMS THEREOF FOR THE CATALYTIC OLIGOMERIZATION OF OLEFINIC MONOMERS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2008-07-03 | — | — | WO | disclosed |
| EP-0320227-B1 | Method of preventing polymer-scale formation | SHINETSU CHEMICAL CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| CN-1023324-C | Method of preventing polymer-scale formation | SHINETSU CHEMICAL CO (JP) | 1993-12-29 | — | — | CN | disclosed |
| US-4933399-A | COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| CN-1035118-A | A kind of method that forms polymer-scale that stops | SHINETSU CHEMICAL CO (JP) | 1989-08-30 | — | — | CN | disclosed |
| EP-0320227-A2 | Method of preventing polymer-scale formation | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4250005-A | Radiation cross-linked polyurethane foams | SCOTT PAPER COMPANY (US) | 1981-02-10 | — | — | US | disclosed |
| US-4051078-A | CURING | DAINICHI-NIPPON CABLES, LTD. (JA) | 1977-09-27 | — | — | US | disclosed |
| US-4046744-A | Thermosetting coatings based on ketoxime-blocked isocyanates and oxazolidines | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018200-A1 | COMPOSITION CONTAINING A PHENANTHRENOL | CUTA, AHR, TYR | ALDH1A1 4116/4885HSD17B10 3094/4885HIF1A 1832/4885 |
| US-20140296339-A1 | SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY | SLC6A4, HTR4, GPR34 | ALDH1A1 3075/4885HSD17B10 3677/4885HIF1A 402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.