SCHEMBL28034269

SCHEMBL28034269

CCCC(C(=O)OC(C)(C)C)C(O)C(N)=O.NC1CC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 2/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
CTSK P43235 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8017449 0.73 CA1 (0.36) NOS1NOS3NOS2CTSKCA1
SCHEMBL12098467 0.70 CHRM1 (0.38) NOS1NOS3NOS2CTSKCA1
SCHEMBL15015760 0.70 CHRM1 (0.40) NOS1NOS3NOS2CTSKCA1
SCHEMBL12321026 0.70 CTSK (0.36) NOS1NOS3NOS2CTSKCA1
SCHEMBL27435004 0.69 NOS1 (0.38) NOS1NOS3NOS2CTSKCA2
SCHEMBL28732870 0.69 CA1 (0.41) NOS1NOS3NOS2CTSKCA1
SCHEMBL14275185 0.69 NOS1 (0.36) NOS1NOS3NOS2CA1CA2
SCHEMBL23151921 0.68 NOS1 (0.39) NOS1NOS3NOS2CTSKCA1
Methylamine SCHEMBL28388761 0.68 NOS1 (0.39) NOS1NOS3NOS2CTSKCA1
SCHEMBL30571827 0.67 CHRM1 (0.38) NOS1NOS3NOS2CTSKCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105085310-A New synthesis method of telaprevir intermediate CHONGQING HUIZHI PHARMACEUTICAL RES INST CO LTD 2015-11-25 CN disclosed