SCHEMBL28034291

SCHEMBL28034291

CCC(=O)Oc1cn(C(=O)OC)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.56
MEN1 O00255 1/20 0.56
AKR1C3 P42330 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NR4A2 P43354 2/20 0.42
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.40
THRB P10828 1/20 0.40
GAA P10253 1/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 3/20 0.39
CREBBP Q92793 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28466414 0.82 KMT2A (0.54) KMT2AMEN1L3MBTL1ALDH1A1KDM4E
SCHEMBL10842053 0.82 KMT2A (0.65) KMT2AMEN1AKR1C3L3MBTL1LMNA
SCHEMBL28034933 0.80 NR4A2 (0.49) KMT2AMEN1LMNASMN1; SMN2NR4A2
SCHEMBL28034943 0.78 NR4A2 (0.55) KMT2AMEN1L3MBTL1LMNASMN1; SMN2
SCHEMBL6848608 0.78 KMT2A (0.63) KMT2AMEN1AKR1C3L3MBTL1LMNA
SCHEMBL28879342 0.76 L3MBTL1 (0.59) KMT2AMEN1L3MBTL1CREBBP
SCHEMBL15747688 0.74 L3MBTL1 (0.60) KMT2AMEN1AKR1C3L3MBTL1LMNA
SCHEMBL8076273 0.74 KMT2A (0.67) KMT2AMEN1L3MBTL1LMNASMN1; SMN2
SCHEMBL8076272 0.74 KMT2A (0.67) KMT2AMEN1AKR1C3L3MBTL1LMNA
SCHEMBL10842060 0.74 KMT2A (0.67) KMT2AMEN1AKR1C3L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104936591-B Hematopoietin expression facilitator 国立大学法人东北大学 2018-05-29 CN disclosed
CN-104936591-A Erythropoietin expression promoter UNIV TOHOKU NAT UNIV CORP 2015-09-23 CN disclosed