SCHEMBL28034933

SCHEMBL28034933

CCC(=O)Oc1cn(C)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.49
ALDH1A1 P00352 4/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
MITF O75030 1/20 0.48
MAPT P10636 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
MEN1 O00255 1/20 0.47
KDM4E B2RXH2 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
IDO1 P14902 1/20 0.45
POLB P06746 1/20 0.45
GPR84 Q9NQS5 1/20 0.45
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28095904 0.89 NR4A2 (0.48) NR4A2ALDH1A1KMT2ALMNAMITF
SCHEMBL1122106 0.83 PRKCA (0.47) NR4A2KMT2AMEN1KDM4E
SCHEMBL28034943 0.83 NR4A2 (0.55) NR4A2ALDH1A1KMT2ALMNAMAPT
SCHEMBL3416860 0.82 NR4A2 (0.53) NR4A2ALDH1A1KMT2ALMNAMITF
SCHEMBL10698031 0.82 NR4A2 (0.53) NR4A2ALDH1A1KMT2ALMNAMITF
SCHEMBL28034304 0.81 CNR2 (0.56) ALDH1A1KDM4E
SCHEMBL8500052 0.81 NR4A2 (0.51) NR4A2ALDH1A1KMT2ALMNAMITF
SCHEMBL28034291 0.80 KMT2A (0.56) NR4A2ALDH1A1KMT2ALMNAMAPT
SCHEMBL2350154 0.79 NR4A2 (0.50) NR4A2ALDH1A1KMT2ALMNAMITF
SCHEMBL28034295 0.79 CDC25A (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104936591-A Erythropoietin expression promoter UNIV TOHOKU NAT UNIV CORP 2015-09-23 CN disclosed