Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666908 | 0.90 | PHLPP2 (0.66) | GAAALDH1A1PHLPP2BCHEMAPT | |
| Hydrochloric Acid SCHEMBL27693811 | 0.89 | PHLPP2 (0.64) | GAAALDH1A1PHLPP2BCHEMAPT | |
| SCHEMBL9629064 | 0.88 | GAA (0.84) | GAAALDH1A1PHLPP2MAPTTDP1 | |
| SCHEMBL19688301 | 0.84 | TDP1 (0.59) | ALDH1A1TDP1LMNACYP1A2MAPK1 | |
| SCHEMBL11287086 | 0.83 | GAA (0.71) | GAAALDH1A1PHLPP2MAPTTDP1 | |
| SCHEMBL14924442 | 0.82 | GAA (0.74) | GAAALDH1A1PHLPP2MAPTTDP1 | |
| Isonicotinic Acid Butyl Ester SCHEMBL4312059 | 0.81 | LMNA (0.67) | ALDH1A1MAPTTDP1LMNACYP1A2 | |
| SCHEMBL5452825 | 0.81 | GAA (0.72) | GAAALDH1A1PHLPP2MAPTTDP1 | |
| SCHEMBL11641497 | 0.81 | PHLPP2 (0.82) | GAAALDH1A1PHLPP2MAPTLMNA | |
| SCHEMBL15953935 | 0.80 | L3MBTL1 (0.59) | ALDH1A1MAPTTDP1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981458-A | Inhibitors of histone demethylases | EPITHERAPEUTICS APS | 2015-10-14 | — | — | CN | disclosed |