Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2512299 | 0.93 | BBOX1 (0.61) | BBOX1KMT2AATMBCHEACHE | |
| Bicarbonate SCHEMBL5911592 | 0.88 | BBOX1 (0.57) | BBOX1KMT2AATMBCHEACHE | |
| Bicarbonate SCHEMBL2704202 | 0.86 | BBOX1 (0.59) | BBOX1KMT2AATMBCHEACHE | |
| Acetic Acid SCHEMBL1056731 | 0.86 | BBOX1 (0.59) | BBOX1KMT2AATMBCHEACHE | |
| Bicarbonate SCHEMBL2836768 | 0.84 | BBOX1 (0.57) | BBOX1KMT2AATMBCHEACHE | |
| Acrylic Acid SCHEMBL2526435 | 0.84 | BBOX1 (0.57) | BBOX1KMT2AATMBCHEACHE | |
| Hydrochloric Acid SCHEMBL28273648 | 0.83 | BBOX1 (0.39) | BBOX1KMT2AATMACHEALDH1A1 | |
| Succinic Acid SCHEMBL28710003 | 0.82 | BBOX1 (0.71) | BBOX1KMT2AATMBCHEACHE | |
| Acrylic Acid SCHEMBL11323113 | 0.82 | BBOX1 (0.55) | BBOX1KMT2AATMBCHEACHE | |
| Acrylic Acid SCHEMBL578283 | 0.82 | BBOX1 (0.55) | BBOX1KMT2AATMBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104857867-B | CO2 separating membrane having both primary amine and carbonate and preparation method thereof | 天津大学 | 2017-04-26 | — | — | CN | disclosed |
| CN-104857867-A | Carbon dioxide separating membrane having both primary amine and carbonate and preparation method thereof | UNIV TIANJIN | 2015-08-26 | — | — | CN | disclosed |