Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2836768 | 0.98 | BBOX1 (0.57) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL5911592 | 0.93 | BBOX1 (0.57) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL2512299 | 0.92 | BBOX1 (0.61) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acetic Acid SCHEMBL1056731 | 0.90 | BBOX1 (0.59) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL2704201 | 0.90 | BBOX1 (0.52) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL2526435 | 0.88 | BBOX1 (0.57) | BBOX1KMT2AATMALDH1A1ACHE | |
| Succinic Acid SCHEMBL28710003 | 0.86 | BBOX1 (0.71) | BBOX1KMT2AATMACHEBCHE | |
| Acrylic Acid SCHEMBL11323113 | 0.86 | BBOX1 (0.55) | BBOX1KMT2AATMALDH1A1ACHE | |
| Bicarbonate SCHEMBL28034606 | 0.86 | BBOX1 (0.55) | BBOX1KMT2AATMALDH1A1ACHE | |
| Acrylic Acid SCHEMBL578283 | 0.86 | BBOX1 (0.55) | BBOX1KMT2AATMALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120107415-A1 | COMBINED DISINFECTION AND DECONTAMINATION AGENT HAVING INCREASED EFFECTIVENESS | MULTIBIND BIOTEC GMBH (DE) | 2012-05-03 | — | — | US | claimed |
| US-6436878-B1 | COPOLYMER OF ACRYLIC ACID, 2-HYDROXYPROPYL ACRYLATE, N-(4-SULFOPHENYL)-MALEIMIDE, ALLYLTRIMETHYLAMMONIUM CHLORIDE AND APHOSPHOROUS ACID | Wang, Bin (CN) | 2002-08-20 | — | — | US | claimed |
| EP-2540686-B1 | Fiber for fiber cement and resulting product | WEYERHAEUSER NR CO (US) | 2016-11-30 | — | — | EP | disclosed |
| US-8999399-B2 | Combined disinfection and decontamination agent having increased effectiveness | Bose Chemie GmbH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-8461233-B2 | Fiber for fiber cement and resulting product | WEYERHAEUSER NR COMPANY (US) | 2013-06-11 | — | — | US | disclosed |
| US-20130005859-A1 | Fiber for Fiber Cement and Resulting Product | WEYERHAEUSER NR COMPANY (US) | 2013-01-03 | — | — | US | disclosed |
| EP-2540686-A1 | Fiber for fiber cement and resulting product | Weyerhaeuser Company (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120107415-A1 | COMBINED DISINFECTION AND DECONTAMINATION AGENT HAVING INCREASED EFFECTIVENESS | MULTIBIND BIOTEC GMBH (DE) | 2012-05-03 | — | — | US | disclosed |
| WO-2008035101-A2 | DISINFECTANT EMULSIONS CONTAINING AN ANTIMICROBIAL COMPOUND IN EACH PHASE | MAINSANI AS (NO) | 2008-03-27 | — | — | WO | disclosed |
| US-6436878-B1 | COPOLYMER OF ACRYLIC ACID, 2-HYDROXYPROPYL ACRYLATE, N-(4-SULFOPHENYL)-MALEIMIDE, ALLYLTRIMETHYLAMMONIUM CHLORIDE AND APHOSPHOROUS ACID | Wang, Bin (CN) | 2002-08-20 | — | — | US | disclosed |