Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28731479 | 0.98 | — | — | |
| Sulfuric Acid SCHEMBL28164355 | 0.89 | KDM6B (0.32) | — | |
| Ammonia Solution, Strong SCHEMBL28121422 | 0.87 | KDM6B (0.35) | — | |
| SCHEMBL220872 | 0.85 | KDM6B (0.37) | — | |
| Chloromethane SCHEMBL28035194 | 0.83 | KDM6B (0.33) | — | |
| Hydrochloric Acid SCHEMBL28192366 | 0.83 | KDM6B (0.35) | — | |
| Chloromethane SCHEMBL5491655 | 0.81 | KDM6B (0.34) | — | |
| SCHEMBL27547589 | 0.80 | ALDH1A1 (0.39) | — | |
| Trimethylammonium SCHEMBL2379186 | 0.77 | TET2 (0.31) | — | |
| Methacrylic Acid SCHEMBL4594667 | 0.77 | KDM6B (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111378-B | A kind of cationic polymer Grafted Nano-scale avicel cellulose and its preparation method and application | 赵迎辉 | 2018-01-09 | — | — | CN | disclosed |
| CN-105237648-B | A kind of glyoxal cross-linked polymer is modified high amylopectin starch and its preparation method and application | 赵迎辉 | 2017-08-01 | — | — | CN | disclosed |
| CN-105237648-A | Highly-branched starch modified by glyoxal crosslinked polymer, preparation method and application thereof | ZHAO YINGHUI | 2016-01-13 | — | — | CN | disclosed |
| CN-105111378-A | Cationic polymer grafting modified nanocrystalline cellulose and preparation method and application thereof | ZHAO YINGHUI | 2015-12-02 | — | — | CN | disclosed |
| CN-105086322-A | Glyoxal cross-linked polymer modified nano crystalline cellulose as well as preparation method and application thereof | ZHAO YINGHUI | 2015-11-25 | — | — | CN | disclosed |