SCHEMBL28034810

SCHEMBL28034810

C=C(C)C(=O)OOC(=O)c1ccccc1C(=O)OC(O)CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
ALDH1A1 P00352 7/20 0.37
CYP3A4 P08684 3/20 0.36
CA2 P00918 1/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TP53 P04637 1/20 0.35
MAPK1 P28482 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
ELANE P08246 1/20 0.33
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1595729 0.85 ALDH1A1 (0.37) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL10528768 0.84 TSHR (0.37) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL1513963 0.83 TSHR (0.53) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL9801403 0.82 NPC1 (0.47) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL30730734 0.80 TSHR (0.66) TSHRALDH1A1CYP3A4LMNAKDM4E
SCHEMBL466072 0.80 TSHR (0.66) TSHRALDH1A1CYP3A4LMNAKDM4E
Phthalic Acid SCHEMBL27818266 0.78 ALDH1A1 (0.42) TSHRALDH1A1CA2LMNAKDM4E
SCHEMBL10591636 0.77 TSHR (0.52) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL1513969 0.77 ALDH1A1 (0.56) TSHRALDH1A1CYP3A4CA2LMNA
SCHEMBL873754 0.77 TSHR (0.50) TSHRALDH1A1CA2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105008411-A BLOCKED ISOCYANATO GROUP-CONTAINING POLYMER, COMPOSITION CONTAINING POLYMER, AND APPLICATIONS THEREOF SHOWA DENKO KK 2015-10-28 CN disclosed