Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034810 | 0.82 | TSHR (0.39) | NPC1CA2ALDH1A1KDM4EHPGD | |
| SCHEMBL1595729 | 0.82 | ALDH1A1 (0.37) | NPC1CA2ALDH1A1KDM4EHPGD | |
| SCHEMBL30125534 | 0.82 | KDM4E (0.51) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL21271559 | 0.82 | ALDH1A1 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28938366 | 0.82 | KDM4E (0.51) | CA1CA2CA9ALDH1A1KDM4E | |
| SCHEMBL137907 | 0.81 | NPC1 (0.62) | NPC1PDCD1CD274CA12CA1 | |
| SCHEMBL10528768 | 0.80 | TSHR (0.37) | CA2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL22164112 | 0.79 | NPC1 (0.57) | NPC1PDCD1CD274CA12CA1 | |
| SCHEMBL8453228 | 0.79 | NPC1 (0.43) | NPC1HPGDTSHRRAB9ALMNA | |
| SCHEMBL696763 | 0.79 | TSHR (0.43) | NPC1PDCD1CD274ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985474-A | PLUGGING HOLES IN PRINTED CIRCUIT BOARDS | SOMAR CORPORATION (JP) | 1991-01-15 | — | — | US | claimed |
| US-4985474-A | PLUGGING HOLES IN PRINTED CIRCUIT BOARDS | SOMAR CORPORATION (JP) | 1991-01-15 | — | — | US | disclosed |