Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614060 | 0.78 | KCNMA1 (0.41) | HDAC8KCNMA1 | |
| SCHEMBL15882889 | 0.76 | CA2 (0.48) | NOTUM | |
| SCHEMBL9204355 | 0.75 | HTT (0.49) | CHRM1MAPTPLA2G1BATG4BTTR | |
| SCHEMBL1514806 | 0.74 | CHRM1 (0.46) | KCNMA1CHRM1MAPTPLA2G1BATG4B | |
| SCHEMBL16982962 | 0.72 | KCNMA1 (0.54) | HDAC8KCNMA1NOTUMMRGPRX4LMNA | |
| SCHEMBL30994998 | 0.72 | NOTUM (0.52) | HDAC8KCNMA1NOTUMMARS1 | |
| SCHEMBL16753902 | 0.72 | NOTUM (0.52) | HDAC8KCNMA1NOTUMMARS1 | |
| SCHEMBL6053268 | 0.72 | CHRM1 (0.46) | CHRM1MAPTPLA2G1BATG4BTTR | |
| SCHEMBL28034215 | 0.72 | SLC6A2 (0.42) | CHRM1MAPTPLA2G1BATG4BTTR | |
| SCHEMBL2820469 | 0.72 | BRD4 (0.66) | NOTUMHPGDSLC6A2SLC6A3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373969-B | Phenyl azoles ring substituted amide compounds and its production and use | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-09-16 | — | — | CN | disclosed |