SCHEMBL635208

SCHEMBL635208

CCCCCNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.70
CA12 O43570 1/20 0.66
CA2 P00918 1/20 0.66
CA9 Q16790 1/20 0.66
ALOX15 P16050 1/20 0.64
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
HTT P42858 2/20 0.60
MBTD1 Q05BQ5 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
LMNA P02545 3/20 0.58
MAPK1 P28482 1/20 0.57
PKM P14618 2/20 0.57
GAA P10253 1/20 0.57
MAPT P10636 1/20 0.57
ALOX12 P18054 1/20 0.57
ALB P02768 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635949 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL28034898 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL633648 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL634183 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL5696735 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL223156 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL7103280 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL8355315 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL634180 0.98 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15
SCHEMBL187922 0.95 ALDH1A1 (0.72) ALDH1A1CA12CA2CA9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102180825-B Method for preparing 3-indole arylmethanesulfonamide UNIV SUZHOU 2013-11-13 CN claimed
CN-118439980-B Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2025-04-08 CN disclosed
CN-118439980-A Synthesis method of alpha-cyano sulfonamide derivative 浙江工业大学 2024-08-06 CN disclosed
CN-116375611-A Method for synthesizing difluoroalkyl compound from fatty amine 浙江工业大学 2023-07-04 CN disclosed
EP-2389352-B1 ARGINASE INHIBITORS AND METHODS OF USE UNIV PENNSYLVANIA (US) 2019-05-08 EP disclosed
CN-109336888-A A kind of derivative and preparation method and application containing three azepine * of benzo and pyrazolone structure parent nucleus 南昌大学 2019-02-15 CN disclosed
EP-2302000-B1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORP (JP) 2016-11-16 EP disclosed
CN-104428300-B The suppression of enzyme 奇斯药制品公司 2016-11-09 CN disclosed
US-9051501-B2 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2015-06-09 US disclosed
EP-2100923-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2013-03-13 EP disclosed
US-8008386-B2 Curable composition KANEKA CORPORATION (JP) 2011-08-30 US disclosed
EP-2302000-A1 Curable composition and catalyst composition KANEKA CORPORATION (JP) 2011-03-30 EP disclosed
US-20100063215-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-03-11 US disclosed
US-20100041810-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION KANEKA CORPORATION (JP) 2010-02-18 US disclosed
EP-2100923-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-09-16 EP disclosed
EP-2088173-A1 CURABLE COMPOSITION AND CATALYST COMPOSITION Kaneka Corporation (JP) 2009-08-12 EP disclosed
CN-1101807-C Hydroxamic acid derivs. NOVARTIS AG (CH) 2003-02-19 CN disclosed
CN-1232447-A Hydroxamic acid derivs. NOVARTIS AG (CH) 1999-10-20 CN disclosed
US-4053458-A INHIBITORS UOP INC. (US) 1977-10-11 US disclosed
US-4022828-A BIS-(SULFONAMIDO)-SULFIDES UNIVERSAL OIL PRODUCTS COMPANY (US) 1977-05-10 US disclosed