Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 2/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL6339732 | 0.94 | ALDH1A1 (0.88) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL27778625 | 0.94 | ALDH1A1 (0.88) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL28180817 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL1074283 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL17745 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL30537001 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL6061130 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL30536983 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL28491203 | 0.94 | ALDH1A1 (1.00) | ALDH1A1KMT2AMEN1SRD5A2TDP1 | |
| Benzophenone SCHEMBL23175179 | 0.90 | ALDH1A1 (0.93) | ALDH1A1KMT2AMEN1SRD5A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-216538433-U | Benzophenone serialization production system | 重庆长风化学工业有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-105289242-B | Sustained release neutralization method for hydrogen chloride gas | 重庆长风化学工业有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-105330526-A | Raw material for preparation of diphenyl ketone | Chongqing changfeng chemical industry co ltd | 2016-02-17 | — | — | CN | disclosed |
| CN-105198723-A | Preparation method of benzophenone | Chongqing changfeng chemical industry co ltd | 2015-12-30 | — | — | CN | disclosed |