Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703738 | 0.82 | ENPP2 (0.46) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL7930396 | 0.82 | ENPP2 (0.41) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL2318890 | 0.78 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL3988450 | 0.78 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL16984910 | 0.78 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL29392408 | 0.76 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL28083714 | 0.76 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL9131 | 0.76 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL5987894 | 0.75 | ENPP2 (0.45) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL10269835 | 0.75 | GAA (0.37) | ENPP2TSHRACHEORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903296-A | Dihydropyrazole GPR40 modulators | BRISTOL MYERS SQUIBB CO | 2015-09-09 | — | — | CN | disclosed |