Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.40 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299770 | 0.87 | ORAI1 (0.47) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL14703738 | 0.86 | ENPP2 (0.46) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL28035120 | 0.82 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL3988450 | 0.82 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL16984910 | 0.82 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL2318890 | 0.82 | ENPP2 (0.39) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL28083714 | 0.79 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL29392408 | 0.79 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL9131 | 0.79 | TSHR (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL10269835 | 0.79 | GAA (0.37) | ENPP2TSHRACHEORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020104-A1 | Process for preparing substituted benzyl compounds and toluene derivatives | CLARIANT GMBH | 2001-09-06 | — | — | US | disclosed |
| EP-1127861-A1 | Method to synthesise substituted benzyl and toluene compounds | Clariant GmbH (DE) | 2001-08-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020104-A1 | Process for preparing substituted benzyl compounds and toluene derivatives | NISCH, TBCB, NBAS | ENPP2 4404/4885TSHR 3294/4885ACHE 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.