Tert-Butyl Formate

Tert-Butyl Formate

SCHEMBL28035122

CC(C)(C)OC=O.ClCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.43

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
TAAR1 Q96RJ0 2/20 0.38
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
ABCC4 O15439 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
PTGS1 P23219 1/20 0.38
HTT P42858 1/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
FFAR1 O14842 1/20 0.36
SLC13A5 Q86YT5 1/20 0.36
MME P08473 1/20 0.35
ACE P12821 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
CTSS P25774 1/20 0.35
CTSK P43235 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27794837 0.84 TDP1 (0.62) TDP1LMNAGAATSHR
Tert-Butyl Formate SCHEMBL27502194 0.83 TDP1 (0.43) TDP1TAAR1IDO1AGXTABCC4
Tert-Butyl Formate SCHEMBL28032597 0.82 TDP1 (0.59) TDP1LMNAGAATSHR
Ethoxycarbonyl Group SCHEMBL28035121 0.80 TAAR1 (0.38) TAAR1IDO1AGXTABCC4LMNA
Tert-Butyl Formate SCHEMBL27932186 0.80 IDO1 (0.47) TDP1TAAR1IDO1AGXTLMNA
Tert-Butyl Formate SCHEMBL28290877 0.79 TDP1 (0.50) TDP1LMNATSHR
SCHEMBL28035600 0.78 CSNK2A1 (0.34) TDP1GAA
SCHEMBL1071609 0.78 TAAR1 (0.56) TDP1TAAR1IDO1AGXTABCC4
Water SCHEMBL28351968 0.75 TAAR1 (0.54) TDP1TAAR1IDO1AGXTABCC4
Hydrochloric Acid SCHEMBL28118118 0.75 TAAR1 (0.54) TDP1TAAR1IDO1AGXTABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330541-B The synthetic method of the alkyl formate of 4 ' halogenated methyl biphenyl 2 常州博世伟业生物科技有限公司 2017-09-12 CN disclosed
CN-105330541-A Synthesis method of 4'-halogenated methylbiphenyl-2-formic aid alkyl ester CHANGZHOU BOSHI WEIYE BIOTECHNOLOGY CO LTD 2016-02-17 CN disclosed