Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28035121

CCOC=O.ClCc1ccc(-c2ccccc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.38
IDO1 P14902 2/20 0.38
AGXT P21549 2/20 0.38
ABCC4 O15439 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
PTGS1 P23219 1/20 0.38
HTT P42858 1/20 0.38
FAAH O00519 2/20 0.38
MGLL Q99685 2/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
FFAR1 O14842 1/20 0.36
MAPT P10636 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27961596 0.86 ALDH1A1 (0.41) LMNAGAAL3MBTL1SMN1; SMN2MAPT
Ethoxycarbonyl Group SCHEMBL27558742 0.84 DHODH (0.40) TAAR1LMNAGAAL3MBTL1SMN1; SMN2
Ethoxycarbonyl Group SCHEMBL27687097 0.83 TSHR (0.42) TAAR1IDO1AGXTABCC4LMNA
Tert-Butyl Formate SCHEMBL28035122 0.80 TDP1 (0.43) TAAR1IDO1AGXTABCC4LMNA
SCHEMBL1071609 0.78 TAAR1 (0.56) TAAR1IDO1AGXTABCC4LMNA
Aniline SCHEMBL27426850 0.77 CYP3A4 (0.45) TAAR1IDO1AGXTLMNATSHR
Water SCHEMBL28351968 0.75 TAAR1 (0.54) TAAR1IDO1AGXTABCC4LMNA
Hydrochloric Acid SCHEMBL28118118 0.75 TAAR1 (0.54) TAAR1IDO1AGXTABCC4LMNA
SCHEMBL131472 0.74 IDO1 (0.55) TAAR1IDO1AGXTABCC4LMNA
Chlorobenzene SCHEMBL28088147 0.74 TSHR (0.46) LMNATSHRL3MBTL1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330541-B The synthetic method of the alkyl formate of 4 ' halogenated methyl biphenyl 2 常州博世伟业生物科技有限公司 2017-09-12 CN disclosed
CN-105330541-A Synthesis method of 4'-halogenated methylbiphenyl-2-formic aid alkyl ester CHANGZHOU BOSHI WEIYE BIOTECHNOLOGY CO LTD 2016-02-17 CN disclosed