Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489238 | 0.84 | PTGS1 (0.49) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL29712512 | 0.83 | CSNK2A1 (0.46) | TSHRFFAR1FFAR4FOLH1KMT2A | |
| SCHEMBL3738386 | 0.80 | FFAR1 (0.54) | PTGS1FFAR1FFAR4AKR1B1 | |
| SCHEMBL29191992 | 0.79 | FOLH1 (0.44) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL9978839 | 0.79 | TSHR (0.55) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL29133116 | 0.78 | ALDH1A1 (0.56) | PTGS1KMT2APPARG | |
| SCHEMBL20458937 | 0.77 | PTGS1 (0.53) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL3731501 | 0.77 | FFAR1 (0.54) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL9890663 | 0.77 | PTGS1 (0.59) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL28160677 | 0.77 | FOLH1 (0.71) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330541-A | Synthesis method of 4'-halogenated methylbiphenyl-2-formic aid alkyl ester | CHANGZHOU BOSHI WEIYE BIOTECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |