Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28035133 | 0.84 | PTGS1 (0.49) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL29712511 | 0.83 | ALDH1A1 (0.44) | TSHRFOLH1CES2CES1KMT2A | |
| SCHEMBL175541 | 0.82 | PTGS1 (0.50) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL4664590 | 0.81 | ALDH1A1 (0.41) | LMNATSHRFOLH1CES2CES1 | |
| SCHEMBL9978839 | 0.79 | TSHR (0.55) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL29133116 | 0.78 | ALDH1A1 (0.56) | PTGS1KMT2APPARG | |
| SCHEMBL20458937 | 0.77 | PTGS1 (0.53) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL3731501 | 0.77 | FFAR1 (0.54) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL30461149 | 0.77 | FOLH1 (0.71) | FOLH1CES2CES1KMT2A | |
| SCHEMBL9890663 | 0.77 | PTGS1 (0.59) | PTGS1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330541-A | Synthesis method of 4'-halogenated methylbiphenyl-2-formic aid alkyl ester | CHANGZHOU BOSHI WEIYE BIOTECHNOLOGY CO LTD | 2016-02-17 | — | — | CN | disclosed |
| CN-103382154-B | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-103992276-A | 4'-{[(2,4,5-trisubstituted phenyl)-1H-imidazole-1-yl]methyl}biphenyl-2-formic acid derivatives | JILIN INST OF PHARMACEUTICAL RES | 2014-08-20 | — | — | CN | disclosed |
| CN-102212034-B | Method for preparing telmisartan impurity B | WEIHAI DISU PHARMACEUTICAL CO LTD | 2014-02-26 | — | — | CN | disclosed |
| CN-103382154-A | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2013-11-06 | — | — | CN | disclosed |
| CN-102276585-B | Preparation method for and medicinal usage of 4-substituted-phenyl-aryl-carboxylate derivatives | UNIV CHINA PHARMA | 2013-06-19 | — | — | CN | disclosed |
| CN-102276585-A | Preparation method for and medicinal usage of 4-substituted-phenyl-aryl-carboxylate derivatives | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102212034-A | Method for preparing telmisartan impurity B | WEIHAI DISU PHARMACEUTICAL CO LTD | 2011-10-12 | — | — | CN | disclosed |
| CN-101798287-A | [(4-methyl-2-propyl-N-methoxyl-substituted benzene alkyl-1H-benzimidazole-6-formamide)-1-yl] methyldiphenyl compound and preparation method thereof | BEIJING INST TECHNOLOGY | 2010-08-11 | — | — | CN | disclosed |
| CN-100506799-C | [(2-n-propyl-4-methyl-1H-Benzimidazole)6-radical] carboxamide-1-radical] methylbiphenyl compound, synthesizing method and usage | BEIJING INST TECHNOLOGY (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-100460396-C | Intermediate of telmisartan, its preparation and use | HANGZHOU SHENGMEI MEDICINE SCI (CN) | 2009-02-11 | — | — | CN | disclosed |
| CN-100441567-C | Acrylic ester and methyl acrylic ester kind side chain type luminous polymer and its synthesis | UNIV SUZHOU (CN) | 2008-12-10 | — | — | CN | disclosed |
| CN-101037414-A | [(2-n-propyl-4-methyl-1H-Benzimidazole)6-radical] carboxamide-1-radical] methylbiphenyl compound, synthesizing method and usage | BEIJING INST TECHNOLOGY (CN) | 2007-09-19 | — | — | CN | disclosed |
| CN-101024631-A | Intermediate of telmisartan, its preparation and use | SHENGMEI MEDICINE SCIENCE TECH (CN) | 2007-08-29 | — | — | CN | disclosed |
| CN-1786106-A | Acrylic ester and methyl acrylic ester kind side chain type luminous polymer and its synthesis | UNIV SUZHOU (CN) | 2006-06-14 | — | — | CN | disclosed |
| CN-1256326-C | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 2006-05-17 | — | — | CN | disclosed |
| CN-1202152-A | Novel 4- (oxoxyphenyl) -3-oxopiperidines for the treatment of cardiac and renal insufficiency | HOFFMANN LA ROCHE (CH) | 1998-12-16 | — | — | CN | disclosed |