Ethoxycarbonyl Group

Ethoxycarbonyl Group

SCHEMBL28035162

CCOC=O.Fc1cncc(F)c1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.37
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethoxycarbonyl Group SCHEMBL27323072 0.77 CYP1A2 (0.43) CYP2C9CYP2C19
Ethoxycarbonyl Group SCHEMBL27297885 0.77 CHRNB2 (0.38) HCAR2CYP2C9CYP2C19
SCHEMBL28206091 0.74 HCAR2 (0.48) HCAR2
Pyrazine SCHEMBL27608305 0.72 KMT2A (0.31)
Formic Acid SCHEMBL27858692 0.72 HCAR2 (0.52) HCAR2CYP2C9
Ethoxycarbonyl Group SCHEMBL5306888 0.71 ALDH1A1 (0.38)
Ethoxycarbonyl Group SCHEMBL453 0.71
Ethoxycarbonyl Group SCHEMBL1332384 0.71
SCHEMBL56635 0.71
Formic Acid Methyl Ester SCHEMBL28331389 0.69 ATM (0.42) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108200760-A BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS 英安塔制药有限公司 2018-06-22 CN disclosed
CN-105324385-A Bace inhibitors LILLY CO ELI 2016-02-10 CN disclosed