Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.56 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930048 | 0.85 | TAAR1 (0.64) | TAAR1IDO1ALDH1A1 | |
| SCHEMBL3301625 | 0.85 | TAAR1 (0.59) | TAAR1IDO1DAOAOC3MPO | |
| SCHEMBL8703610 | 0.85 | TAAR1 (0.64) | TAAR1IDO1ALDH1A1 | |
| SCHEMBL11198019 | 0.82 | TAAR1 (0.47) | TAAR1IDO1DAOMPOKDM4E | |
| SCHEMBL11195175 | 0.79 | TAAR1 (0.44) | TAAR1IDO1 | |
| SCHEMBL10515673 | 0.77 | TAAR1 (0.52) | TAAR1IDO1DAOAOC3MPO | |
| SCHEMBL14415629 | 0.76 | TAAR1 (0.75) | TAAR1IDO1AOC3MPO | |
| SCHEMBL11775308 | 0.75 | MPO (0.41) | TAAR1IDO1DAOMPOALDH1A1 | |
| SCHEMBL3891013 | 0.74 | TAAR1 (0.47) | TAAR1IDO1KDM4EALDH1A1 | |
| SCHEMBL4664484 | 0.74 | LMNA (0.46) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107118211-A | The preparation method of the western croak of Leo | 南京斯贝源医药科技有限公司 | 2017-09-01 | — | — | CN | disclosed |
| CN-104892459-A | Riociguat intermediate and preparation method thereof | SUZHOU MIRACPHARMA TECHNOLOGY CO LTD | 2015-09-09 | — | — | CN | disclosed |