Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614409 | 0.88 | HTT (0.40) | KMT2AHTTTLR4CYP1A2NOS3 | |
| SCHEMBL8965184 | 0.86 | CYP1A2 (0.43) | HTTTLR4CYP1A2NOS3NOS1 | |
| SCHEMBL158776 | 0.86 | CYP1A2 (0.43) | HTTTLR4CYP1A2NOS3NOS1 | |
| SCHEMBL8965187 | 0.86 | CYP1A2 (0.43) | HTTTLR4CYP1A2NOS3NOS1 | |
| SCHEMBL8964738 | 0.86 | CYP1A2 (0.43) | HTTTLR4CYP1A2NOS3NOS1 | |
| SCHEMBL8964734 | 0.86 | CYP1A2 (0.43) | HTTTLR4CYP1A2NOS3NOS1 | |
| SCHEMBL8600712 | 0.84 | CYP1A2 (0.46) | HTTCYP1A2 | |
| SCHEMBL9842994 | 0.82 | — | — | |
| Acetic Acid SCHEMBL1482741 | 0.79 | PTGER2 (0.44) | AKR1C4AKR1C3AKR1C2HTTTLR4 | |
| Acetic Acid SCHEMBL18130856 | 0.79 | PTGER2 (0.44) | AKR1C4AKR1C3AKR1C2HTTTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563195-B | Process for producing branched modified rubber, rubber composition comprising branched modified rubber prepared by the process, and use thereof | 公共型股份公司希布尔控股 | 2021-07-27 | — | — | CN | claimed |
| CN-101657475-B | Carboxylate terminated polymer and the purposes in impact-modified plastics thereof | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |