SCHEMBL8965187

SCHEMBL8965187

CCCCC[C@@H]1C(=O)CC[C@H]1C

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.43
PTGER2 P43116 5/20 0.40
PTGER4 P35408 2/20 0.40
PTGER3 P43115 2/20 0.40
ALDH1A1 P00352 1/20 0.40
HTT P42858 2/20 0.37
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NOS1 P29475 3/20 0.36
NOS2 P35228 3/20 0.36
NOS3 P29474 2/20 0.36
TLR4 O00206 1/20 0.36
EPHX1 P07099 1/20 0.34
PRKCA P17252 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8964734 1.00 CYP1A2 (0.43) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
SCHEMBL8965184 1.00 CYP1A2 (0.43) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
SCHEMBL8964738 1.00 CYP1A2 (0.43) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
SCHEMBL158776 1.00 CYP1A2 (0.43) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
SCHEMBL8600712 0.98 CYP1A2 (0.46) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
SCHEMBL1614409 0.94 HTT (0.40) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
Acetic Acid SCHEMBL4134829 0.92 PTGER2 (0.44) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
Acetic Acid SCHEMBL1482741 0.92 PTGER2 (0.44) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
Acetic Acid SCHEMBL18130856 0.92 PTGER2 (0.44) CYP1A2PTGER2PTGER4PTGER3ALDH1A1
Acetic Acid Methyl Ester SCHEMBL28101633 0.87 HTT (0.45) CYP1A2PTGER2PTGER4PTGER3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513627-B1 Tetrahydro-alpha-pyrone derivative, method for its preparation and perfume and/or flavouring compositions containing it GIVAUDAN ROURE INT (CH) 1996-02-28 EP disclosed
US-5248792-A Flavor, odor GIVAUDAN-ROURE CORPORATION (US) 1993-09-28 US disclosed
EP-0513627-A1 Tetrahydro-alpha-pyrone derivative, method for its preparation and perfume and/or flavouring compositions containing it GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1992-11-19 EP disclosed