Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964734 | 1.00 | CYP1A2 (0.43) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL8965187 | 1.00 | CYP1A2 (0.43) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL8965184 | 1.00 | CYP1A2 (0.43) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL158776 | 1.00 | CYP1A2 (0.43) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL8600712 | 0.98 | CYP1A2 (0.46) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| SCHEMBL1614409 | 0.94 | HTT (0.40) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| Acetic Acid SCHEMBL4134829 | 0.92 | PTGER2 (0.44) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| Acetic Acid SCHEMBL1482741 | 0.92 | PTGER2 (0.44) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| Acetic Acid SCHEMBL18130856 | 0.92 | PTGER2 (0.44) | CYP1A2PTGER2PTGER4PTGER3ALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL28101633 | 0.87 | HTT (0.45) | CYP1A2PTGER2PTGER4PTGER3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50250-E1 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | FIRMENICH SA (CH) | 2024-12-31 | — | — | US | disclosed |
| US-11339113-B2 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | FIRMENICH SA (CH) | 2022-05-24 | — | — | US | disclosed |
| US-20210323904-A1 | PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES | FIRMENICH SA (CH) | 2021-10-21 | — | — | US | disclosed |
| EP-3823954-A1 | PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES | Firmenich SA (CH) | 2021-05-26 | — | — | EP | disclosed |
| WO-2020127094-A1 | PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES | FIRMENICH SA (CH) | 2020-06-25 | — | — | WO | disclosed |
| EP-0513627-B1 | Tetrahydro-alpha-pyrone derivative, method for its preparation and perfume and/or flavouring compositions containing it | GIVAUDAN ROURE INT (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5248792-A | Flavor, odor | GIVAUDAN-ROURE CORPORATION (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0513627-A1 | Tetrahydro-alpha-pyrone derivative, method for its preparation and perfume and/or flavouring compositions containing it | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339113-B2 | Process for the preparation of cis-alpha,beta substituted cyclopentanones | CYP4A11, CYP11B1, CYP51A1 | CYP1A2 59/4885PTGER2 1243/4885PTGER4 216/4885 |
| US-20210323904-A1 | PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES | CYP4A11, CYP11B1, CYP51A1 | CYP1A2 59/4885PTGER2 1243/4885PTGER4 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.