Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21217060 | 0.95 | CPN1 (0.41) | CPN1CPB2SIGMAR1HTR2AKCNH2 | |
| SCHEMBL20998290 | 0.88 | CCR2 (0.39) | CPN1CPB2SIGMAR1HTR2AGNAI3 | |
| Iodide SCHEMBL15008323 | 0.87 | KCNH2 (0.33) | CPN1CPB2SIGMAR1KCNH2GNAI3 | |
| Trifluoromethanesulfonic Acid SCHEMBL29251848 | 0.85 | CPN1 (0.39) | CPN1CPB2SIGMAR1DPP7 | |
| SCHEMBL23709494 | 0.84 | CPN1 (0.40) | CPN1CPB2SIGMAR1HTR2ADPP7 | |
| SCHEMBL557956 | 0.84 | CPN1 (0.40) | CPN1CPB2SIGMAR1HTR2ADPP7 | |
| SCHEMBL21226122 | 0.82 | GNAI3 (0.39) | GNAI3GNAO1GNAI1DNM1 | |
| SCHEMBL23717596 | 0.82 | GNAI3 (0.39) | GNAI3GNAO1GNAI1DNM1 | |
| SCHEMBL24822691 | 0.82 | GNAI3 (0.39) | GNAI3GNAO1GNAI1DNM1 | |
| Iodide SCHEMBL15008878 | 0.82 | GNAI3 (0.35) | KCNH2GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008353-A | 2-acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA INC | 2015-10-28 | — | — | CN | disclosed |