Succinimide

Succinimide

SCHEMBL28035341

O=C1CCC(=O)N1.O=Cc1ccc(C(=O)O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
MAPT P10636 2/20 0.47
METAP1 P53582 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
CRBN Q96SW2 3/20 0.45
DDB1 Q16531 1/20 0.45
MYC P01106 1/20 0.45
IL1RN P18510 1/20 0.45
ERAP1 Q9NZ08 1/20 0.45
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
UNG P13051 1/20 0.42
PIM1 P11309 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4633354 0.87 TSHR (0.57) ALDH1A1METAP1HTTCRBNDDB1
SCHEMBL63361 0.82 ALDH1A1 (1.00) ALDH1A1TRIM24TRIM33TDP1KMT2A
Terephthalic Acid SCHEMBL11068404 0.82 ALDH1A1 (1.00) ALDH1A1TRIM24TRIM33TDP1KMT2A
SCHEMBL28508718 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
SCHEMBL29693000 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
SCHEMBL28234323 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
Hydrochloric Acid SCHEMBL740726 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
SCHEMBL8161786 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
SCHEMBL8594185 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A
Ammonia Solution, Strong SCHEMBL10546475 0.80 ALDH1A1 (0.95) ALDH1A1TRIM24TRIM33TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117462693-A XTEN conjugate compositions and methods of making the same 阿穆尼克斯运营公司 2024-01-30 CN disclosed
CN-106029106-A Coagulation factor IX conjugates 诺和诺德保健股份有限公司 2016-10-12 CN disclosed
CN-105979972-A Factor viii conjugates 诺和诺德股份有限公司 2016-09-28 CN disclosed
CN-105802979-A Expression vector and expression method of calf intestinal alkaline phosphatase 科蒂亚(新乡)生物技术有限公司 2016-07-27 CN disclosed
CN-105637088-A COAGULATION FACTOR VII polypeptides NOVO NORDISK HEALTHCARE AG 2016-06-01 CN disclosed
CN-105008530-A Thrombin sensitive coagulation factor X molecules NOVO NORDISK AS 2015-10-28 CN disclosed