Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61919 | 0.89 | CPB2 (0.32) | EPHX1 | |
| SCHEMBL61920 | 0.89 | CPB2 (0.32) | EPHX1 | |
| Pyrene SCHEMBL28162735 | 0.87 | SIRT2 (0.34) | PIN1 | |
| Pyrene SCHEMBL28913773 | 0.79 | CYP1A2 (0.43) | MEN1KMT2A | |
| SCHEMBL5893971 | 0.77 | CPB2 (0.32) | — | |
| SCHEMBL5893967 | 0.77 | CPB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL31172342 | 0.76 | CPB2 (0.31) | — | |
| SCHEMBL16310139 | 0.75 | HDAC6 (0.34) | PIN1 | |
| SCHEMBL30611740 | 0.75 | CPB2 (0.33) | — | |
| SCHEMBL28094778 | 0.75 | KMT2A (0.50) | MEN1KMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085404-B | The pyrene compound of histidine methylester modification and its synthetic method and application | 华南师范大学 | 2017-08-08 | — | — | CN | claimed |
| CN-105085404-A | Pyrene compound modified with dl-histidine monohydrochloride and synthetizing method and application thereof | UNIV SOUTH CHINA NORMAL | 2015-11-25 | — | — | CN | claimed |
| CN-105085404-B | The pyrene compound of histidine methylester modification and its synthetic method and application | 华南师范大学 | 2017-08-08 | — | — | CN | disclosed |
| CN-105085404-A | Pyrene compound modified with dl-histidine monohydrochloride and synthetizing method and application thereof | UNIV SOUTH CHINA NORMAL | 2015-11-25 | — | — | CN | disclosed |