Formic Acid

Formic Acid

SCHEMBL28035547

Nc1ccnc(Cl)c1.O=CO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.42
LOX P28300 1/20 0.42
LOXL3 P58215 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
SMARCA2 P51531 6/20 0.39
SMARCA4 P51532 5/20 0.39
CCNC P24863 1/20 0.38
CDK8 P49336 1/20 0.38
ASIC3 Q9UHC3 1/20 0.37
TRPA1 O75762 1/20 0.35
KCNH2 Q12809 1/20 0.34
SCN5A Q14524 1/20 0.34
SCN9A Q15858 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40039 0.87
SCHEMBL29452955 0.87
Fluoromethane SCHEMBL28852278 0.81 LOX (0.47) RECQLLOXLOXL3LOXL2SMARCA2
Formic Acid SCHEMBL31604295 0.76 UHRF1 (0.45) SMARCA2SMARCA4CCNCCDK8ASIC3
Formic Acid SCHEMBL28204191 0.76 RECQL (0.42) RECQLLOXLOXL3LOXL2SMARCA2
Phenylurea SCHEMBL27479524 0.72 MAPT (0.50) SMARCA2SMARCA4
SCHEMBL4309817 0.71 SMARCA2 (0.42) LOXLOXL3LOXL2SMARCA2SMARCA4
SCHEMBL5488197 0.71 SMARCA2 (0.42) LOXLOXL3LOXL2SMARCA2SMARCA4
Dalfampridine SCHEMBL27520243 0.69 MAPT (0.68) ALDH1A1CYP3A4THRBTSHR
Formic Acid SCHEMBL4630354 0.68 CYP3A4 (0.73) RECQLCA1CA2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104988531-B The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid 浙江工业大学 2017-11-07 CN claimed
CN-104988531-A Method for preparing picolinic acid through electro-catalysis selective dechloridation of chloropicolinicacid UNIV ZHEJIANG TECHNOLOGY 2015-10-21 CN claimed
CN-109415319-A Synthesizing aryl carboxylate is coupled by direct Su Chuji 美国陶氏益农公司 2019-03-01 CN disclosed
CN-104988531-B The method that a kind of selective dechlorination of chloro-pyridine formic acid electro-catalysis prepares pyridine carboxylic acid 浙江工业大学 2017-11-07 CN disclosed
CN-104988531-A Method for preparing picolinic acid through electro-catalysis selective dechloridation of chloropicolinicacid UNIV ZHEJIANG TECHNOLOGY 2015-10-21 CN disclosed