Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309817 | 1.00 | SMARCA2 (0.42) | SMARCA2SMARCA4GRM4LOXLOXL3 | |
| SCHEMBL3736841 | 0.90 | SMARCA2 (0.49) | SMARCA2SMARCA4GRM4LOXLOXL3 | |
| SCHEMBL40039 | 0.77 | — | — | |
| SCHEMBL29452955 | 0.77 | — | — | |
| SCHEMBL1569277 | 0.75 | PIN1 (0.39) | GRM4ROCK1 | |
| Fluoromethane SCHEMBL28852278 | 0.72 | LOX (0.47) | SMARCA2SMARCA4LOXLOXL3LOXL2 | |
| SCHEMBL8061244 | 0.71 | ALDH1A1 (0.52) | CA2 | |
| Formic Acid SCHEMBL28035547 | 0.71 | RECQL (0.42) | SMARCA2SMARCA4LOXLOXL3LOXL2 | |
| SCHEMBL562935 | 0.70 | S1PR2 (0.47) | SMARCA2SMARCA4CHRNB2CHRNA4 | |
| SCHEMBL45336 | 0.69 | ALDH1A1 (0.50) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047793-A2 | CYCLOPENTENOL NUCLEOSIDE COMPOUNDS, INTERMEDIATES FOR THEIR SYNTHESIS AND METHODS OF TREATING VIRAL INFECTIONS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2007-04-26 | — | — | WO | disclosed |