Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490466 | 0.87 | KMT2A (0.42) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL18764366 | 0.85 | SMN1; SMN2 (0.43) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11982021 | 0.81 | SMN1; SMN2 (0.49) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL120535 | 0.80 | TKT (0.46) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL12775821 | 0.77 | KMT2A (0.41) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1520898 | 0.76 | SMN1; SMN2 (0.44) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL6850660 | 0.76 | SMN1; SMN2 (0.42) | TKTKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3116021 | 0.74 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL27905191 | 0.73 | LMNA (0.39) | TKTLMNACYP1A2 | |
| SCHEMBL3116025 | 0.73 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104903296-A | Dihydropyrazole GPR40 modulators | BRISTOL MYERS SQUIBB CO | 2015-09-09 | — | — | CN | disclosed |