SCHEMBL28035575

SCHEMBL28035575

CC(=O)Oc1ncccc1NCC(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK2 Q9HBH9 5/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPT P10636 3/20 0.36
KDM4E B2RXH2 3/20 0.36
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
ABCB11 O95342 1/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
PDE4A P27815 1/20 0.35
ADRA1A P35348 1/20 0.35
OPRK1 P41145 1/20 0.35
STAT6 P42226 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HIF1A Q16665 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372675 0.76 L3MBTL1 (0.49) L3MBTL1KDM4ETDP1LMNAKMT2A
SCHEMBL28035576 0.71 KDM4E (0.40) MKNK2MAPTKDM4ETDP1LMNA
SCHEMBL1291161 0.71 L3MBTL1 (0.43) L3MBTL1MAPTKDM4ECYP3A4TDP1
SCHEMBL814188 0.69 KDM4E (0.42) L3MBTL1MAPTKDM4ECYP3A4TDP1
SCHEMBL4945110 0.69 KDM4E (0.44) L3MBTL1KDM4ECYP3A4TDP1ABCB11
SCHEMBL28806916 0.69 KDM4E (0.44) L3MBTL1MAPTKDM4ECYP3A4TDP1
SCHEMBL10881331 0.69 KDM4E (0.51) KDM4ECYP3A4TDP1ABCB11LMNA
SCHEMBL4945566 0.67 KDM4E (0.54) L3MBTL1KDM4ECYP3A4TDP1ABCB11
SCHEMBL27670976 0.67 KDM4E (0.43) KDM4ECYP3A4TDP1ABCB11LMNA
SCHEMBL27703269 0.67 KDM4E (0.43) L3MBTL1KDM4ECYP3A4TDP1ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102822178-B There is the pyrido thiazine of herbicide effect BASF SE (DE) 2015-10-21 CN disclosed