Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.40 |
| ▸ | HMGCR | P04035 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595476 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL7795312 | 0.92 | TSHR (0.56) | TSHRLMNAALDH1A1KMT2ACA12 | |
| SCHEMBL13892956 | 0.82 | TSHR (0.54) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10794247 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10794256 | 0.81 | TSHR (0.67) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL8596453 | 0.81 | TSHR (0.52) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL8411340 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL12910845 | 0.81 | TSHR (0.52) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL3129143 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR | |
| SCHEMBL10403786 | 0.81 | PTPN7 (0.63) | TSHRLMNAALDH1A1PTPN7HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664604-B | Bromo-9,11,19-tri-alkynes-17, the 21-diene behenic acid Lipase absobed methods of bromination yne compounds E, E-22- | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-04 | — | — | CN | disclosed |