Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922056 | 0.75 | CHRM5 (0.55) | CHRM5CHRM3ALDH1A1TDP1SIGMAR1 | |
| SCHEMBL980475 | 0.75 | CHRM5 (0.46) | CHRM5CHRM3SIGMAR1MEN1KMT2A | |
| SCHEMBL6887723 | 0.73 | CHRM5 (0.53) | CHRM5CHRM3SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8483418 | 0.73 | CHRM5 (0.53) | CHRM5CHRM3ALDH1A1TDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4219766 | 0.73 | CHRM5 (0.53) | CHRM5CHRM3ALDH1A1TDP1SIGMAR1 | |
| SCHEMBL7933593 | 0.73 | CHRM5 (0.53) | CHRM5CHRM3ALDH1A1TDP1SIGMAR1 | |
| SCHEMBL27365152 | 0.73 | SIGMAR1 (0.46) | CHRM5CHRM3KDM4EALDH1A1MAPT | |
| SCHEMBL31377968 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1MAPTTDP1GAA | |
| Ethyl Piperazinoacetate SCHEMBL5699 | 0.72 | SIGMAR1 (0.49) | CHRM5CHRM3ALDH1A1TDP1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27387609 | 0.71 | SIGMAR1 (0.45) | CHRM5CHRM3SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105250221-B | A kind of Licopyrinobuter dried emulsifier and preparation method thereof | 天津药物研究院 | 2018-06-19 | — | — | CN | disclosed |
| CN-105250221-A | Licopyrinobuter dry emulsion and preparation method thereof | TIANJIN INST PHARM RESEARCH | 2016-01-20 | — | — | CN | disclosed |
| CN-103172634-B | 6-(4-chloro-phenyl-)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrroles mile piperazine-5-acetic acid-4 ' preparation method of-bromine butyl ester | TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH (CN) | 2015-09-30 | — | — | CN | disclosed |