Ethyl Piperazinoacetate

Ethyl Piperazinoacetate

SCHEMBL5699

CCOC(=O)CN1CCNCC1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.49
CHRM5 P08912 2/20 0.47
CHRM3 P20309 2/20 0.47
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ELANE P08246 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TRPA1 O75762 1/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
ABL1 P00519 1/20 0.38
RIN1 Q13671 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PIN1 Q13526 1/20 0.38
PIN4 Q9Y237 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethyl Piperazinoacetate SCHEMBL17271810 0.98 SIGMAR1 (0.47) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL8911402 0.98 SIGMAR1 (0.47) SIGMAR1CHRM5CHRM3GSK3AGSK3B
Ethyl Piperazinoacetate SCHEMBL16528281 0.98 SIGMAR1 (0.47) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL8484657 0.98 SIGMAR1 (0.47) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL26091201 0.98 SIGMAR1 (0.47) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL1418858 0.93 SIGMAR1 (0.54) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL31365998 0.92 SIGMAR1 (0.43) SIGMAR1CHRM5CHRM3GSK3AGSK3B
Hydrochloric Acid SCHEMBL22344162 0.92 SIGMAR1 (0.52) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL28466894 0.90 SIGMAR1 (0.48) SIGMAR1CHRM5CHRM3GSK3AGSK3B
SCHEMBL4444447 0.90 SIGMAR1 (0.51) SIGMAR1CHRM5CHRM3ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005633-A Fluorescent probe for detecting threonine tyrosine kinase and preparation method and application thereof 五邑大学 2024-05-10 CN claimed
CN-104046246-B The chemical-mechanical planarization of tungsten-containing substrate 气体产品与化学公司 2016-06-15 CN claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-8835492-B2 Temperature and pH sensitive block copolymer and polymeric hydrogels using the same SUNGYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2014-09-16 US claimed
CN-102838567-A Benzenesulfonyl piperazine compounds or benzoyl piperazine compounds, preparation methods and uses thereof SHENZHEN TONGZHOU ELECTRONIC CO LTD 2012-12-26 CN claimed
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2010-09-16 US claimed
WO-2009031861-A2 TEMPERATURE AND PH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFETY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) 2009-03-12 WO claimed
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR COROPORATE COLLABORATION (KR) 2008-11-27 US claimed
WO-2008130180-A1 PREPARATION OF DRUG DELIVERY SYSTEMS USING PH-SENSITIVE BLOCK COPOLYMER AND THEIR APPLICATION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-10-30 WO claimed
WO-2004108068-A2 4-[4-(4-MORPHOLINO)ANILINO]PYRIMIDINE DERIVATIVES, METHOD FOR PREPARING THEREOF AND ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING THE SAME B & C BIOPHARM CO., LTD. (KR) 2004-12-16 WO claimed
CN-1072661-C Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 2001-10-10 CN claimed
CN-1215395-A Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 1999-04-28 CN claimed
CN-122036736-A Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application 云南大学 2026-05-15 CN disclosed
EP-4159727-B1 INHIBITORS OF (ALPHA-V)(BETA-6) INTEGRIN MORPHIC THERAPEUTIC INC (US) 2026-04-08 EP disclosed
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery UNIV JOHNS HOPKINS (US) 2026-04-02 US disclosed
US-4009167-A SILVER HALIDE SOLVENTS, PHOTOGRAPHY POLAROID CORPORATION (US) 1977-02-22 US disclosed
US-3976647-A PHOTOGRAPHIC SILVER HALIDE SOLVENTS POLAROID CORPORATION (US) 1976-08-24 US disclosed
US-3962247-A ANGINA PECTORIS FUJI CHEMICAL INDUSTRY CO., LTD. (JA) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233264-A1 TEMPERATURE AND pH-SENSITIVE BLOCK COPOLYMER HAVING EXCELLENT SAFTY IN VIVO AND HYDROGEL AND DRUG DELIVERY SYSTEM USING THEREOF CD44, PSAT1, ALAD SIGMAR1 1171/4885CHRM5 4340/4885CHRM3 4284/4885
US-20080293827-A1 Temperature and Ph Sensitive Block Copolymer and Polymeric Hydrogels Using the Same LRBA, DAO, PAM SIGMAR1 1134/4885CHRM5 2046/4885CHRM3 3014/4885
US-20260092134-A1 Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery SLC43A1, SLC7A5, SLC7A1 SIGMAR1 311/4885CHRM5 4707/4885CHRM3 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.