Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 5/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA7 | P43166 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL28035979 | 1.00 | LMNA (0.71) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| Benzyl Fumarate SCHEMBL8936637 | 0.95 | HCAR2 (0.79) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| Styrene SCHEMBL28875192 | 0.90 | LMNA (0.61) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL6391956 | 0.88 | HCAR2 (0.56) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL6391964 | 0.88 | HCAR2 (0.56) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL8377990 | 0.88 | LMNA (0.77) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL8377988 | 0.88 | LMNA (0.77) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL357565 | 0.88 | HCAR2 (0.89) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL337503 | 0.88 | HCAR2 (0.89) | LMNAHCAR2AKR1B10AKR1B1CA12 | |
| SCHEMBL337504 | 0.88 | HCAR2 (0.89) | LMNAHCAR2AKR1B10AKR1B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085804-B | Polystyrene butenedioic acid dibenzyl ester and preparation method and application thereof | 中国石油天然气股份有限公司 | 2018-02-02 | — | — | CN | disclosed |
| CN-105085804-A | Polystyrene butenedioic acid dibenzyl ester and preparation method and application thereof | PETROCHINA CO LTD | 2015-11-25 | — | — | CN | disclosed |