SCHEMBL28035616

SCHEMBL28035616

OCc1[c]ccc(OC(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 5/20 0.37
FFAR4 Q5NUL3 3/20 0.33
FFAR1 O14842 2/20 0.33
CETP P11597 1/20 0.33
RUNX1 Q01196 1/20 0.33
CYP2C9 P11712 1/20 0.33
SCN5A Q14524 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
PIM1 P11309 1/20 0.33
KIF11 P52732 1/20 0.33
MAPT P10636 1/20 0.33
EPHX2 P34913 1/20 0.33
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575515 0.82 GPR3 (0.37) GPR3CYP2C9SCN5AKDM4EGAA
SCHEMBL27969355 0.82 GPR3 (0.37) GPR3CYP2C9SCN5AGAAKIF11
SCHEMBL3093135 0.82 GPR3 (0.37) GPR3KIF11
SCHEMBL3076523 0.76 GPR3 (0.40) GPR3CETPCYP2C9SCN5AGAA
SCHEMBL622940 0.73 GPR3 (0.41) GPR3CETPCYP2C9SCN5AKDM4E
SCHEMBL407346 0.73 GPR3 (0.41) GPR3FFAR4CYP2C9SCN5AKDM4E
SCHEMBL9934560 0.73 ALDH1A1 (0.44) GAAKMT2A
SCHEMBL5183831 0.73 MAPT (0.37) GPR3KDM4EMAPTEPHX2
SCHEMBL20721999 0.72 PDE2A (0.35) KMT2A
SCHEMBL538958 0.72 GPR3 (0.41) GPR3FFAR4CYP2C9SCN5AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103958484-B Oxazolidinone derivative, preparation method and medical application thereof SHANGHAI HENGRUI PHARMACEUTICAL CO.,LTD. (CN) 2015-11-25 CN disclosed