Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 9/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 8/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036128 | 0.89 | JAK2 (0.47) | JAK2MAP4K3METALK | |
| SCHEMBL28628304 | 0.86 | MET (0.45) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28643808 | 0.83 | MET (0.47) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28646124 | 0.83 | JAK2 (0.42) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28628229 | 0.83 | JAK2 (0.40) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28515206 | 0.82 | JAK2 (0.62) | JAK2MAP4K3MET | |
| SCHEMBL3687014 | 0.82 | MET (0.48) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28642048 | 0.82 | MET (0.46) | JAK2MAP4K3METALKFYN | |
| SCHEMBL28924806 | 0.80 | JAK2 (0.44) | JAK2MAP4K3METALK | |
| SCHEMBL1823431 | 0.80 | MET (0.57) | JAK2MAP4K3METALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968654-A | Substituted 2-aminopyridine protein kinase inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2015-10-07 | — | — | CN | disclosed |