Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28238507 | 0.95 | PTGES (0.54) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL28983027 | 0.85 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL17905720 | 0.83 | KDM4E (0.65) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL20225797 | 0.81 | TSHR (0.63) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL3673447 | 0.81 | PTGS1 (0.63) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL11603858 | 0.80 | ALOX5 (0.61) | CYSLTR2CYSLTR1SMPD1ALDH1A1LMNA | |
| SCHEMBL27859167 | 0.80 | TP53 (0.59) | LMNATSHRPLA2G4B | |
| SCHEMBL12810301 | 0.80 | TSHR (0.59) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL16766527 | 0.80 | PTGES (0.48) | CYSLTR2CYSLTR1SMPD1KDM4EALDH1A1 | |
| SCHEMBL11499290 | 0.79 | ALOX5 (0.54) | CYSLTR2CYSLTR1SMPD1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981452-A | Skin whitening agent containing novel cyclic compound | RNS CO LTD | 2015-10-14 | — | — | CN | disclosed |