SCHEMBL28035877

SCHEMBL28035877

NCc1ccc([C@H](O)CBr)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.44
TAAR1 Q96RJ0 3/20 0.43
HTR3A P46098 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
HIF1A Q16665 1/20 0.43
HRH3 Q9Y5N1 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALOX15 P16050 1/20 0.42
APEX1 P27695 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LOXL2 Q9Y4K0 5/20 0.41
F10 P00742 1/20 0.39
F11 P03951 1/20 0.39
AOC3 Q16853 3/20 0.36
NOS3 P29474 1/20 0.36
NOS1 P29475 1/20 0.36
NOS2 P35228 1/20 0.36
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27718584 1.00 ABAT (0.44) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL4284221 0.82 TAAR1 (0.64) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL28036350 0.82 ENPP2 (0.48) NFKB1LOXL2NOS3NOS1NOS2
SCHEMBL28036349 0.82 ENPP2 (0.48) NFKB1LOXL2NOS3NOS1NOS2
Hydrochloric Acid SCHEMBL3669220 0.80 APEX1 (0.65) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL27577466 0.80 ABAT (0.46) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL27543042 0.78 ABAT (0.44) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL6612632 0.78 LMNA (0.56) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL27404752 0.78 ABAT (0.44) ABATTAAR1HTR3ATSHRNFKB1
SCHEMBL4410797 0.77 ABAT (0.52) ABATTAAR1HTR3ATSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104961626-B A kind of preparation method of hydroxyl bromine compounds 中国科学院化学研究所 2016-09-21 CN disclosed
CN-104961626-A Hydroxyl bromine compound preparation method CHINESE ACAD INST CHEMISTRY 2015-10-07 CN disclosed