Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | HPGDS | O60760 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916025 | 0.84 | HTT (0.72) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL621880 | 0.81 | ALDH1A1 (0.56) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8058635 | 0.81 | ALDH1A1 (0.47) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL29991874 | 0.81 | ALDH1A1 (0.56) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3841710 | 0.81 | PDGFRB (0.46) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL13666129 | 0.80 | ALDH1A1 (0.55) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL31033500 | 0.80 | ALDH1A1 (0.55) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL558148 | 0.80 | ALDH1A1 (0.55) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL557973 | 0.80 | NCF1 (0.59) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL30891066 | 0.80 | TLR9 (0.50) | RAB9AALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103524436-B | 1-[(the alkoxyl group quinoxalinyl that 6,7-replaces) aminocarboxyl]-4-(mixing) aryl piperazine derivative | REXAHN PHARMACEUTICALS INC. (US) | 2015-09-23 | — | — | CN | disclosed |