SCHEMBL28035930

SCHEMBL28035930

CCCc1cccc(OCc2ccccc2O)c1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.51
CYP4A11 Q02928 1/20 0.51
MAOB P27338 4/20 0.48
ABCB1 P08183 5/20 0.46
BCHE P06276 6/20 0.45
HTR1A P08908 2/20 0.45
DRD2 P14416 2/20 0.45
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2293090 0.82 CYP4F2 (0.48) CYP4F2CYP4A11MAOBABCB1BCHE
SCHEMBL19912586 0.81 ABCB1 (0.47) CYP4F2CYP4A11ABCB1HTR1ADRD2
SCHEMBL327570 0.81 CYP4F2 (0.70) CYP4F2CYP4A11MAOBABCB1BCHE
SCHEMBL8702737 0.81 ABCB1 (0.49) CYP4F2CYP4A11ABCB1HTR1ADRD2
SCHEMBL2292614 0.79 MAOA (0.47) CYP4F2CYP4A11MAOBABCB1BCHE
SCHEMBL5708170 0.77 CYP4F2 (0.64) CYP4F2CYP4A11MAOBABCB1BCHE
SCHEMBL28035917 0.76 HSPA5 (0.50) HTR1A
SCHEMBL31172132 0.76 MAOB (0.62) MAOB
SCHEMBL28615363 0.76 MAOB (0.62) MAOB
SCHEMBL6061336 0.76 F2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed