SCHEMBL28035917

SCHEMBL28035917

CCCc1cccc(Cc2ccccc2O)c1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.50
KEAP1 Q14145 1/20 0.50
CNR1 P21554 2/20 0.46
CNR2 P34972 2/20 0.46
HTR1A P08908 1/20 0.45
BCL2 P10415 1/20 0.44
BCL2L1 Q07817 1/20 0.44
ALOX5 P09917 2/20 0.44
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41
MPO P05164 3/20 0.40
TAAR1 Q96RJ0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28036391 0.90 CNR1 (0.50) HSPA5KEAP1CNR1CNR2HPGD
SCHEMBL8607999 0.87 HSPA5 (0.65) HSPA5KEAP1BCL2BCL2L1ALOX5
SCHEMBL8861038 0.84 HTR2A (0.46) CNR1CNR2ALOX5MEN1KMT2A
SCHEMBL8087029 0.82 TAAR1 (0.42) CNR1CNR2MTNR1AMTNR1BTAAR1
SCHEMBL13256353 0.80 HSPA5 (0.61) HSPA5KEAP1BCL2BCL2L1ALOX5
SCHEMBL28392650 0.79 ALOX15 (0.57) KEAP1CNR1CNR2BCL2BCL2L1
SCHEMBL10339590 0.79 HSPA5 (0.71) HSPA5KEAP1BCL2BCL2L1ALOX5
SCHEMBL5424543 0.79 MTNR1A (0.47) CNR1CNR2MEN1KMT2AMTNR1A
SCHEMBL2578699 0.79 MAPT (0.54) HSPA5KEAP1CNR1CNR2BCL2
SCHEMBL921907 0.78 KEAP1 (0.62) HSPA5KEAP1BCL2BCL2L1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed