SCHEMBL28035960

SCHEMBL28035960

CC(C)(C)c1ccc(CSOSCc2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.49
ACHE P22303 2/20 0.49
EPHX1 P07099 4/20 0.44
APP P05067 1/20 0.42
DAO P14920 1/20 0.41
TSHR P16473 2/20 0.41
KCNH2 Q12809 1/20 0.40
TP53 P04637 1/20 0.40
LMNA P02545 1/20 0.39
TYR P14679 1/20 0.39
SCN5A Q14524 2/20 0.39
SCN9A Q15858 2/20 0.39
GRIN2C Q14957 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2E1 P05181 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27890285 0.79 BCHE (0.49) BCHEACHEEPHX1APPDAO
SCHEMBL28107526 0.78 IDO1 (0.53) BCHEACHEDAOCA1CA2
SCHEMBL5520434 0.77 BCHE (0.47) BCHEACHEEPHX1APPDAO
SCHEMBL9860976 0.76 BCHE (0.48) BCHEACHEEPHX1DAOCA1
SCHEMBL4269004 0.76 BCHE (0.46) BCHEACHEEPHX1APPDAO
SCHEMBL7693962 0.76 BCHE (0.46) BCHEACHEEPHX1APPDAO
SCHEMBL5520432 0.76 BCHE (0.46) BCHEACHEEPHX1APPDAO
SCHEMBL31325112 0.76 EPHX1 (0.49) BCHEACHEEPHX1APPDAO
SCHEMBL975422 0.75 IDO1 (0.48) BCHEACHECYP1A2ALDH1A1
SCHEMBL7850367 0.75 IDO1 (0.48) ACHEDAOTSHRTP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103172967-B For the Solid mixture antioxidant and preparation method thereof of resin Changzhou University (CN) 2015-10-28 CN claimed
CN-107857717-A Aryl sulfoxid es, sulfide compound and its synthetic method and application 华东师范大学 2018-03-30 CN disclosed
CN-103880723-B A kind of method preparing dibenzyl sulfide ether product 常州大学 2016-08-17 CN disclosed
CN-103172967-B For the Solid mixture antioxidant and preparation method thereof of resin Changzhou University (CN) 2015-10-28 CN disclosed