SCHEMBL9860976

SCHEMBL9860976

CC(C)(C)c1ccc(CSOS(=O)(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.48
ACHE P22303 1/20 0.48
EPHX1 P07099 4/20 0.43
MITF O75030 1/20 0.40
P4HB P07237 1/20 0.39
CA2 P00918 4/20 0.39
CA1 P00915 3/20 0.39
GRIA4 P48058 1/20 0.39
CA9 Q16790 1/20 0.39
EPHX2 P34913 2/20 0.38
NR1H4 Q96RI1 2/20 0.38
DAO P14920 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NR4A2 P43354 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9861052 0.86 SHBG (0.46) BCHEACHEEPHX1ALDH1A1
SCHEMBL28736653 0.83 IDO1 (0.47) BCHEACHECA2CA1CA9
SCHEMBL9861014 0.83 HMGCR (0.36) BCHEACHEALDH1A1RXRARXRB
SCHEMBL9861771 0.81 IDO1 (0.43) CA2DAOALDH1A1RXRARXRB
SCHEMBL9861031 0.81 BCHE (0.44) BCHEACHECA2CA1CA9
SCHEMBL9861753 0.78 BCHE (0.49) BCHEACHEEPHX1CA2CA1
SCHEMBL10859332 0.77 IDO1 (0.43) BCHEACHEEPHX1CA2CA1
SCHEMBL5078812 0.77 CYP2C19 (0.40) BCHEACHECA2CA1CA9
SCHEMBL9861383 0.77 BCHE (0.41) BCHEACHECA2CA1CA9
SCHEMBL28035960 0.76 BCHE (0.49) BCHEACHEEPHX1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150168-B1 USE OF METAL SALTS OF THIOSULPHURIC -S-ESTERS AS RUBBER/METAL BONDING PROMOTERS MONSANTO EUROPE S.A./N.V. (BE) 1991-05-08 EP disclosed
US-4581297-A STEEL BELTED RADIAL TIRES MONSANTO EUROPE, S.A. (BE) 1986-04-08 US disclosed
EP-0150168-A2 Use of metal salts of thiosulphuric -S-esters as rubber/metal bonding promoters MONSANTO EUROPE S.A./N.V. (BE) 1985-07-31 EP disclosed